Using Renal Elastography Measurements for Evaluation of Glomerulonephritis Patients

Using Renal Elastography Measurements for Evaluation of Glomerulonephritis Patients

All participants will clinically evaluated by history taking, full physical examination including body weight and assessment of fluid status, and blood and urine samples for lab analysis (serum creatinine, urea, sodium, potassium, corrected calcium, phosphorous, estimated glomerular filtration rate(GFR) by Cokcroft equation ((140 - age ) x body weight by Kg/creatinine by µmol )complete urine analysis including microscopic examination of urine , 24 hours urinary protein , haemoglobin level .

All participants will undergo renal shear wave elastography measurements. Values will be obtained from the upper, middle, and lower zones of each kidney. A total of six shear wave elastography measurements will be collected to get mean elastography values (MEVs) of each participant.

We will collect results of MEV plus blood and urine samples of each participant then data will undergo statistical analysis to compare between MEV of healthy persons and biopcy proven glomerulonephritis patients

a-inclusion criteria :

• adult patients aged 18 years old or more

• patients diagnosed as glomerulonephritis ( biopcy proven ) and not started specific tratement in Assiut University Hospitals

  b. Exclusion criteria:

• patient with urinary tract obstruction

• patient who has GN and started corticosteroid and/or immunosuppressive drugs

• patient who has congenital anomalies in renal system