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Elastography is a developing technique to assess tissue elasticity. It is software that can be integrated to the ultrasonography machines. Shear wave Elastography (SWE) is an Elastography technique that does not require external pressure on the tissue and supplies quantitative data. It uses real-time short-duration acoustic push pulse to generate shear waves that propagate perpendicular to the main ultrasound beam. When the waves hit the targeted tissue, the tissue is "pushed" in the direction of propagation, causing it to temporarily deform or displace. The ultrasound scanner can monitor the tissue displacement, measuring the time-to-peak displacement and the recovery time. Shear wave velocity increases in diseased tissues, which can be significantly stiffer than normal ones. The parameters are expressed in pressure units of kilopascals (kPa) and velocity (m s-1). SWE have been used to study breast, thyroid, prostate and liver diseases. However, the application of SWE in assessment of renal fibrosis in CKD patients is still unclear.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal subjects | |||
| Diseased subjects |
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| Measure | Description | Time Frame |
|---|---|---|
| The primary outcome of the study is the difference in renal SWE values between normal subjects and CKD patients . | From 2 to 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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CKD patients which ages from 18 to 75 years old
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