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| Name | Class |
|---|---|
| University of Alcala | OTHER |
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Introduction: Several studies have evaluated and confirmed the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance. However, it remains to be elucidated how CYP1A2 polymorphism influences the acute effects of caffeine on this type of exercise.
Objectives: The present study aims to analyze the effects of acute caffeine intake on muscular strength, power, and endurance performance according to CYP1A2 polymorphism in men and women.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Genotype AA - Male - Caffeine | Experimental |
| |
| Genotype AC or CC - Male - Caffeine | Experimental |
| |
| Genotype AA - Male - Placebo | Placebo Comparator |
| |
| Genotype AC or CC - Male - Placebo | Placebo Comparator |
| |
| Genotype AA - Female - Caffeine | Experimental |
| |
| Genotype AC or CC - Female - Caffeine | Experimental |
| |
| Genotype AA - Female - Placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Caffeine | Dietary Supplement | Acute caffeine intake (3 mg/kg) |
|
| Measure | Description | Time Frame |
|---|---|---|
| cyp1a2 polymorphism | Using saliva sample and PCR | Before the beginning of the trial |
| Mean velocity at different %1RM | Measuring bar mean velocity desplacement during bench press and back squat exercises. | Through study completion, an average of 2 weeks |
| Peak velocity at different %1RM | Measuring bar peak velocity and time to reach peak velocity of bar desplacement during bench press and back squat exercises. | Through study completion, an average of 2 weeks |
| Mean power output at different %1RM | Measuring during bench press and back squat exercises. | Through study completion, an average of 2 weeks |
| Peak power output and time to reach peak power output at different %1RM | Measuring during bench press and back squat exercises. | Through study completion, an average of 2 weeks |
| Number of repetitions performed in 1 set at 65%1RM until task failure | In bench press and back squat exercises | Through study completion, an average of 2 weeks |
| Bar velocity deplacement performed in 1 set at 65%1RM until task failure | In bench press and back squat exercises | Through study completion, an average of 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Mood state (tension, depression, anger, vigor, fatigue and confusion) | Participants graded a set of 29 items related to the mood on a Likert scale from 0 (not at all) to 4 (extremely) in reply to the question: How do you feel at this moment? to assess six scales: tension, depression, anger, vigor, fatigue and confusion. | Through study completion, an average of 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá | Alcalá de Henares | Madrid | 28805 | Spain | ||
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| ID | Term |
|---|---|
| D002110 | Caffeine |
| ID | Term |
|---|---|
| D014970 | Xanthines |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D011688 | Purinones |
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| Genotype AC or CC - Female - Placebo | Placebo Comparator |
|
| Placebo | Dietary Supplement | Placebo (3 mg/kg maltodextrin) |
|
| Power output generated in 1 set at 65%1RM until task failure | In bench press and back squat exercise | Through study completion, an average of 2 weeks |
| Maximal Fat Oxidation Rate (MFO) | g/min (MFO) using a metabolic chart. | Through study completion, an average of 2 weeks |
| Resting Metabolic Rate (RMR) | Kcal at rest (RMR) using a metabolic chart. | Through study completion, an average of 2 weeks |
| Adverse effects | perception of power, endurance, energy and exertion, as well as heart, muscular and gastrointestinal discomfort | Through study completion, an average of 2 weeks |
| handgrip and isometric mid-thigh pull tests | N generated | Through study completion, an average of 2 weeks |
| Vertical Jump (cm) | Through study completion, an average of 2 weeks |
| Vertical Jump (power) | Through study completion, an average of 2 weeks |
| Facultad de Medicina y Ciencias de la Salud. Universidad de Alcalá |
| Alcalá de Henares |
| Madrid |
| Spain |
| D011687 |
| Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |