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| ID | Type | Description | Link |
|---|---|---|---|
| 2022-GSP-GG-29 | Other Grant/Funding Number | National High Level Hospital Clinical Research Funding |
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In this study, we aimed to analyze the association between left ventricular mass index and clinical outcomes to provide the potential indicator for worse survival.
This retrospective study aimed to determine the prognostic value of left ventricular mass index in predicting clinical outcomes, including all-cause death, new-onset or recurrent atrial fibrillation, and a composite endpoint of all-cause death, heart failure,permanent pacemaker implantation, new-onset or recurrent atrial fibrillation, and stroke.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Obstructive hypertrophic cardiomyopathy who underwent septal myectomy | Patients who had at least one cardiac magnetic resonance examination before surgery. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Patients had a higher left ventricular mass index or not （the exact value is determined by the cut-off value for the clinical outcomes) | Other | Patients were grouped by the cutoff value of left ventricular mass index (LVMI) for all cause death, and the Maximally Selected Rank Statistics method was used to determine the optimal cutoff point of LVMI for death. |
| Measure | Description | Time Frame |
|---|---|---|
| All-cause death | Any death observed one month after discharge. | One month after discharge |
| Measure | Description | Time Frame |
|---|---|---|
| composite endpoint | Composite endpoint included all-cause death, and nonfatal adverse events, with nonfatal adverse events defined as rehospitalization for heart failure, permanent pacemaker implantation, new-onset or recurrent atrial fibrillation, and stroke. | One month after discharge |
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Inclusion Criteria:(1) Difficulty in relieving symptoms with medication or recurrent syncope. (2) Left ventricular outflow tract (LVOT) pressure gradient ≥ 50 mmHg at rest or with provocation and the maximum thickness of the septum is ≧ 15 mm.
Exclusion Criteria:
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oHCM who underwent septal myectomy and had at least one CMR image before surgery.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai hospital | Beijing | Beijing Municipality | 100037 | China |
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| ID | Term |
|---|---|
| D002312 | Cardiomyopathy, Hypertrophic |
| ID | Term |
|---|---|
| D009202 | Cardiomyopathies |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D001020 | Aortic Stenosis, Subvalvular |
| D001024 | Aortic Valve Stenosis |
| D000082862 | Aortic Valve Disease |
| D006349 | Heart Valve Diseases |
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