Functional Capacity and Quality of Life Following Septal Myectomy in Patients With HCM

Functional Capacity and Quality of Life Following SePtal Myectomy in patIents With Obstructive hypeRtrophIc cardiomyopaThy

Investigators aim to assess changes in exercise capacity and quality of life after septal myectomy in patient with hypertrophic cardiomyopathy.

The objective of this study is to examine change in quality of life and functional capacity as respectively measured by, Quality of Life Questionnaires and six-minute walk test distance, following septal myectomy in patients with obstructive hypertrophic cardiomyopathy, as compared to prior to surgery.

Inclusion Criteria:

• Scheduled to undergo septal myectomy.
• Established diagnosis of obstructive HCM defined as:

LVH Thickness ≥15mm left ventricular outflow tract gradient ≥50mmHg

Exclusion Criteria:

• Prior septal myectomy or alcohol septal ablation
• Prior myocardial infarction
• Uncontrolled arrhythmias including ventricular tachycardia and atrial fibrillation
• Uncontrolled hypertension
• Angiographically documented coronary stenosis >50%, if available at time of screening
• Inability to provide informed consent
• Inability to walk without assistive devices
• Peripheral artery disease with claudication