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| ID | Type | Description | Link |
|---|---|---|---|
| 2022-GSP-GG-29 | Other Grant/Funding Number | National High Level Hospital Clinical Research Funding |
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This study investigated the impact of myocardial bridging (MB) and its characteristics on preoperative atrial fibrillation and survival in patients with obstructive hypertrophic cardiomyopathy (oHCM). We recruited 968 consecutive patients with oHCM who underwent myectomy at our institution between January 2015 and December 2019, including 144 patients with MB and 824 patients without MB. All patients received angiography before surgery. The diagnosis of preoperative atrial fibrillation was based on 12-lead electrocardiography, 24-hour Holter electrocardiography, or in-hospital electrocardiogram monitoring, which was extracted from patients' medical records. Surgical details and follow-up data were also collected.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Obstructive hypertrophic cardiomyopathy who underwent septal myectomy | All patients underwent angiography and without other coronary artery disease. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coronary artery bypass grafting or unroofing | Procedure | Patients had an MB with >75% compression degree would receive coronary artery bypass grafting, and those who underwent unroofing may had a depth of MB < 5mm (whether deal with these MB with a depth <5mm depends on the surgeon and the period time of patients received a surgery). |
| Measure | Description | Time Frame |
|---|---|---|
| All-cause death | Any death occurred one month after discharge | One month after discharge |
| Measure | Description | Time Frame |
|---|---|---|
| New-onset AF | Patients did not have AF before surgery, and AF occurred one month after discharge. | One month after discharge. |
| Composite endpoints | Composite endpoints including all-cause death, new-onset AF, and readmission due to heart failure, stroke, and other cardiovascular events (such as myocardial infarction, arrhythmia). |
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Inclusion Criteria:I(i) age ≥ 18 years and (ii) diagnosis of oHCM based on clinical and echocardiographic evaluation.
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Exclusion Criteria: (i) a history of heart surgery (ii) Patients who had coronary atherosclerosis or myocardial infraction; (iii) Patients who had no angiography records.
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Patients diagnosed with obstructive hypertrophic cardiomyopathy who underwent septal myectomy.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fuwai Hospital | Beijing | Please Select | 475 | China |
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| ID | Term |
|---|---|
| D054084 | Myocardial Bridging |
| D002312 | Cardiomyopathy, Hypertrophic |
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D003330 | Coronary Vessel Anomalies |
| D006330 | Heart Defects, Congenital |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D001026 | Coronary Artery Bypass |
| ID | Term |
|---|---|
| D009204 | Myocardial Revascularization |
| D006348 | Cardiac Surgical Procedures |
| D013504 | Cardiovascular Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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|
| One month after discharge |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D009202 | Cardiomyopathies |
| D001020 | Aortic Stenosis, Subvalvular |
| D001024 | Aortic Valve Stenosis |
| D000082862 | Aortic Valve Disease |
| D006349 | Heart Valve Diseases |
| D001145 | Arrhythmias, Cardiac |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D058017 | Vascular Grafting |
| D014656 | Vascular Surgical Procedures |
| D019616 | Thoracic Surgical Procedures |