Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Myocardial Bridge Bypass Graft surgery is introduced to relieve the unmedical symptoms of patients with long-segment or deep myocardial bridge, clinical outcomes will be collected to verify the effectiveness of the surgery.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MyocardialBridge Bypass Graft | Experimental | The patients with deep(depth>2mm) and long-segement(length>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography. |
|
| Myocardialbridge CABG | Active Comparator | The patients with deep(depth>2mm) and long-segement(length>25mm) of myocardialbridge will be allocated to receive myocardialbridge bypass graft surgery(MBBG)，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The moderate-to-severe atherosclertotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography. |
|
| Myocardioalbridge Unroof | Active Comparator | The patients with superficial type(depth<2mm) and short-segement(length<25mm) of myocardial bridge will be allocated to receive "unroof" surgery，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry end of the myocardialbridge confirmed by coronory artery angiography. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MBBG | Procedure | The patients with deep(depth>2mm) and long-segement(length>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. No atherosclerotic plaque or merely mild atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography. |
| Measure | Description | Time Frame |
|---|---|---|
| All-Cause Mortality | Up to 240 months | |
| Rate of counduit patency | Up to 180 months |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhen Wang, Doctorate | Contact | +86-029-68302464 | wang.zhen@000516.cn | |
| Jinzhou Zhang, Doctorate | Contact | +86-029-68302464 | zhang.jinzhou@000516.cn |
| Name | Affiliation | Role |
|---|---|---|
| Zhen Wang, Doctorate | Xi'an International Medical Center Hospital Affiliated To Northwest University | Principal Investigator |
| Jinzhou Zhang, Doctorate | Xi'an International Medical Center Hospital Affiliated To Northwest University |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Xi'an International Medical Center Hospital Affiliated TO Northwest University | Recruiting | Xi'an | Shaanxi | 710100 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33482166 | Result | Zhang JZ, Zhu GY, Zhang Y, Bai LJ, Wang Z. Myocardial Bridge Bypass Graft: A Novel Surgical Procedure for Extensive Myocardial Bridges. Ann Thorac Surg. 2021 Aug;112(2):e115-e117. doi: 10.1016/j.athoracsur.2020.11.055. Epub 2021 Jan 20. |
| Label | URL |
|---|---|
| The report of the preliminary short term clinical results of MBBG surgery for the first time in the world | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| MB CABG | Procedure | The patients with deep(depth>2mm) and long-segement(length>25mm) of myocardialbridge receiving myocardialbridge bypass graft surgery(MBBG)，fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The moderate-to-severe atherosclerotic stenosis is detected at the proximal or entry of the myocardialbridge confirmed by coronory artery angiography. |
|
| MB unroof | Procedure | The patients with superficial type(depth<2mm) and short-segement(length<25mm) of myocardial bridge will be allocated to receive myocardialbridge "unroof" surgery，when fulfilling the following criteria: 1.presenting with pectoris angina that cannot be effectively relieved by maximum guideline-directed drug therapy; 2. The MB was superficial and short confirmed by coronory artery CT angiography. |
|
| Jinzhou Zhang, Doctorate | Xi'an International Medical Center Hospital Affiliated To Northwest University | Study Chair |
| ID | Term |
|---|---|
| D054084 | Myocardial Bridging |
| D009203 | Myocardial Infarction |
| D017202 | Myocardial Ischemia |
| D060050 | Angina, Stable |
| D016757 | Death, Sudden, Cardiac |
| ID | Term |
|---|---|
| D003330 | Coronary Vessel Anomalies |
| D006330 | Heart Defects, Congenital |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D014652 | Vascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D000787 | Angina Pectoris |
| D002637 | Chest Pain |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D006323 | Heart Arrest |
| D003645 | Death, Sudden |
| D003643 | Death |
Not provided
Not provided