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Comparison of Target Controlled Infusion Anesthesia and Inhalation Anesthesia in Pediatric Laparoscopic Surgeries
In pediatric age group patients undergoing laparoscopic surgery, total intravenous anesthesia (TIVA) and inhalation anesthesia methods are used as anesthesia methods in the intraoperative period; It is compared in terms of its effects on blood pressure, pulse, postoperative awakening time and awakening agitation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Total Intravenous Anesthesia Group | Patients will undergo anesthesia induction as routine after premedication. Once the target BIS level is reached (40-60) and muscle relaxation is achieved, the airway will be secured with an appropriately sized endotracheal tube or laryngeal mask (LMA). The effect zone target concentration of propofol will be adjusted to 3 mcg/ml with the HKI device. Patients will receive controlled ventilation with 50% oxygen/air, and mechanical ventilation parameters will be adjusted so that the end tidal carbon dioxide level (EtCO2) is 35-45 mmHg. |
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| Inhalation Anesthesia Group | Patients will undergo anesthesia induction as routine after premedication. The level of sevoflurane, an inhalation gas, will be adjusted so that BIS values are between 40-60. Patients will receive controlled ventilation with 50% oxygen/air, and mechanical ventilation parameters will be adjusted so that the end tidal carbon dioxide level (EtCO2) is 35-45 mmHg. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Target Controlled Infusion | Device | TCI (Target Controlled Infusion) is a method used to maintain the dose and rate of anesthesia drugs within a target concentration range set by the anesthetist. This system delivers drugs intravenously to the patient using a computer-controlled pump. The anesthetist adjusts the drug concentration to achieve the desired depth of anesthesia. This method provides more precise control over anesthesia and facilitates maintaining the depth of anesthesia within the desired range. |
| Measure | Description | Time Frame |
|---|---|---|
| Modified Aldrete Scoring System | The effects on recovery were monitored within the first hour of the postoperative period using the Modified Aldrete Scoring System (MASS). Totally 0-10 points can be given by MASS. Higher scores predicts better recovery. | Aftet surgery 1 hour |
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure (mmHg) | The blood pressure of the patients will be measured and recorded in mmHg at five-minute intervals from the beginning until the first postoperative hour. | After surger 1 hour |
| Heart rate (beats/minute) |
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Inclusion Criteria:
Exclusion Criteria:
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Children aged 3-12 with ASA I-II undergoing laparoscopic surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Özlem OZ GERGIN, MD | Contact | 09005332466396 | oozgergin@erciyes.edu.tr |
| Name | Affiliation | Role |
|---|---|---|
| Özlem OZ GERGİN, MD | TC Erciyes University | Study Director |
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| ID | Term |
|---|---|
| D018685 | Anesthetics, Inhalation |
| D000077149 | Sevoflurane |
| ID | Term |
|---|---|
| D018681 | Anesthetics, General |
| D000777 | Anesthetics |
| D002492 | Central Nervous System Depressants |
| D045505 | Physiological Effects of Drugs |
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| Inhalation anesthetic | Drug | In the inhalation anesthesia group, maintenance sevoflurane anesthesia will be applied after routine induction. |
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The heart rate of the patients will be measured and recorded in mmHg at five-minute intervals from the beginning until the first postoperative hour.
| After surgey 1 hour |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D002491 | Central Nervous System Agents |
| D045506 | Therapeutic Uses |
| D008738 | Methyl Ethers |
| D004987 | Ethers |
| D009930 | Organic Chemicals |
| D006845 | Hydrocarbons, Fluorinated |
| D006846 | Hydrocarbons, Halogenated |
| D006838 | Hydrocarbons |