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Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome. Therefore, an increased effectiveness of TKE is interesting for physical therapy implication. Besides, adding sensory input which is audible cues or rhythm during exercise may enhance the efficacy of the exercise by increasing neuromuscular control and function.
Therefore, the study aimed to investigate the immediate effects of combined TKE with audible cues on motor unit behavior. The researchers expect that adding rhythm from the metronome will enhance neuromuscular control which may change motor unit behavior of VM muscle. The findings of the study may have helped explain the mechanism behind the acute effects of combined TKE with audible cues on VM function and their potential application in the field of physical therapy.
This study aims to investigate the immediate effect of combined TKE with audible cues on motor unit behavior in healthy participants and to investigate reliability of decomposition electromyography procedure during single leg squat.
A metronome will be used to provide rhythmic exercise. Participants will stand with their feet in line with their shoulders as starting position and straping at the knee. Exercise intensity is 60% of the 1RM weight. At the beginning of the exercise, participants will be asked to bend their knees following the pull of the resistance and exert force to straighten the knee (10 times/set and 3 sets). 180 seconds of resting will be allowed between sets.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental group | Experimental | Terminal Knee Extension Exercise with Audible Cues |
|
| Control group | Active Comparator | Terminal Knee Extension Exercise without Audible Cues |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise + Audible Cues | Behavioral | Combined Terminal Knee Extension Exercise with Audible Cues |
|
| Measure | Description | Time Frame |
|---|---|---|
| Motor unit firing rate | one parameter to explain the motor unit behavior of vastus medialis muscle | At the end of Cycle 1 (each cycle is 1 day) |
| Peak motor action potential | one parameter to explain the motor unit behavior of vastus medialis muscle | At the end of Cycle 1 (each cycle is 1 day) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Physical Therapy, Mahidol University | Nakhon Pathom | Salaya | 73170 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41402906 | Derived | Suntornon P, Kiratisin P, Sinsurin K, Nitkotom S, Sonsukong A, Thong-On S, Watcharakeunkhan P, Sakunkaruna T. Exercise synchronized with audible cues preserves motor unit action potential: a randomized control trial study. BMC Sports Sci Med Rehabil. 2025 Dec 17;18(1):64. doi: 10.1186/s13102-025-01490-y. |
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| ID | Term |
|---|---|
| D018908 | Muscle Weakness |
| ID | Term |
|---|---|
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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There are 2 groups in the current study including exercise with and without audible cues.
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Participant group
| Exercise | Behavioral | Terminal Knee Extension Exercise |
|
| D009422 | Nervous System Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012816 | Signs and Symptoms |