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| ID | Type | Description | Link |
|---|---|---|---|
| 2022-A01957-36 | Other Identifier | IDRCB ANSM |
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Patients presenting to the emergency department with acute dyspnea undergo arterial blood gas measurement and monitoring of transcutaneous capnography using the TCM5 monitor. The aim of this study is to determine whether GapCO2, the difference between transcutaneous and arterial pCO2 (PaCO2 - PtcCO2), is correlated with the congestive or non-congestive origin of dyspnea.
Upon arrival at the emergency department, patients are placed in the vital emergency reception area for monitoring. An emergency physician will review the selection criteria and offer the patient participation. The information sheet will be provided to the patient along with a copy of the non-opposition form in case of patient agreement.
Before the introduction of any treatment, a TC 92 sensor is placed on the earlobe (or on the forehead if the earlobe is inaccessible), connected to a Radiometer TCM5 monitor, measuring SpO2 (Massimo technology), perfusion index, and transcutaneous capnography (PtcCO2).
After a 5-minute equilibration period, measurements were taken throughout the duration of patient management. Standard diagnostic and therapeutic management will be provided according to the attending physician's prescription. The attending physician won't consider PtcCO2 (nor GapCO2) measurements in patient management.
At the time of data analysis, an adjudication committee comprising 2 emergency physicians from the inclusion service but not involved in patient care will review the complete medical records of patients to determine whether dyspnea was of congestive or non-congestive origin.
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| Measure | Description | Time Frame |
|---|---|---|
| GapCO2 | PaCO2 measured via arterial blood gas analysis - PtcCO2 measured via TCM5 monitor, at 37°C | Within 1 hour after enrolment |
| Measure | Description | Time Frame |
|---|---|---|
| Diagnostic performance of GapCO2 at 37°C | Within 1 hour after enrolment | |
| Proportion of patients who underwent GapCO2 measurement among those who presented to the emergency department for dyspnea on the days of inclusion | Feasibility of measuring GapCO2 in the emergency department |
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Inclusion Criteria:
Exclusion Criteria:
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Patient presenting to the emergency department of the inclusion center for acute dyspea
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Judith GORLICKI, MD | Contact | +33 (0)1 48 95 57 85 | judith.gorlicki@aph.fr | |
| Frédéric ADNET, MD-PhD | Contact | +33 (0)1 48 95 57 85 | frederic.adnet@aphp.fr |
| Name | Affiliation | Role |
|---|---|---|
| Judith GORLICKI, MD | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Emergency Department Hospital Avicenne | Recruiting | Bobigny | 93000 | France |
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| ID | Term |
|---|---|
| D004417 | Dyspnea |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
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| up to 28 days |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |