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| ID | Type | Description | Link |
|---|---|---|---|
| 1R01ES034749-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Environmental Health Sciences (NIEHS) | NIH |
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The goal of this randomized control trial is to learn if box fans and filters can reduce asthma symptoms and improve indoor air quality in children ages 6 - 17 years old with asthma living in the Duwamish Valley, Seattle, Washington. The main question it aims to answer are:
Participants will
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sham filter | Experimental | Participants in this arm will receive a sham filter for their box fans. These filters receive a MERV rating of 1 and only filter very large particles and debris such as lint, hair and insects. These particles have little to no impact on asthma symptoms. MERV stands for "minimum efficiency reporting value" and a filter receives a MERV rating as determined by the American Society of Heating, Refrigeration, and Air-Conditioning Engineers. |
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| MERV 13 filter | Experimental | Participants in this arm will receive a MERV 13 filter for their box fans. MERV 13 filters trap the majority of small particles, as small as 1 micron. It also traps up to 75% of particles that are as small as 0.3 microns. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| MERV 13 filter | Other | This is an environmental intervention consisting of a low-cost box fan with a MERV 13 filter placed behind it. The company Lasko makes these fans and other environmental appliances. |
| Measure | Description | Time Frame |
|---|---|---|
| Asthma symptoms | Symptoms are evaluated with the seven-item asthma control questionnaire (ACQ), a validated tool used in children. | ACQ will be measured weekly for 6 consecutive weeks, two pre-intervention weeks (before box fans have been given to participant) and four weeks while fans are being used in the home. Symptoms will also be assessed at the six month follow-up visit. |
| FEV1 | FEV1 is captured with a digital peak flow meter. | FEV1 measures will be taken daily, once in the morning and once at night for the six week study time frame. Prior to the six month follow up we will ask participants to take three consecutive days of FEV1 measurements, for an additional 6 measures |
| Measure | Description | Time Frame |
|---|---|---|
| Asthma quality of life | Will be assessed with the15-item mini-asthma quality of life questionnaire, a validated tool | Will be evaluated at baseline (visit 1), after 6 weeks (visit 3) and at 6 month follow up (visit 4) |
| Use of rescue medications |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Anjum Hajat, PhD, MPH | Contact | 206-685-3618 | anjumh@uw.edu |
| Name | Affiliation | Role |
|---|---|---|
| Anjum Hajat, PhD, MPH | University of Washington | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duwamish River Community Coaltion | Recruiting | Seattle | Washington | 98108 | United States |
Only de-identified individual level data sets will be shared. Given the small sample size of our study, we will protect against deductive disclosure by withholding information that could result in disclosure.
We will also require interested investigators to provide a proposal that will outline their study question and analytic methods. If there is any overlap with ongoing manuscripts, we will ask investigators to collaborate with ongoing efforts or to propose an alternative study question. Investigators will be required to sign a data sharing agreement that will include assurances about participant privacy and data confidentiality.
We do not anticipate a great number of requests for our data so will handle them on an individual basis. After discussing the data with investigators who are interested in accessing it, we will share it via a secure site.
Health data from our randomized control trial will be shared with interested investigators after the two main results papers from the study have been accepted for publication (one on asthma outcomes and the other on air quality). Since data collection will not be finished until year four of the study and the analysis and writing will take some time, data sharing will likely occur after the grant period has ended.
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| Sham filter | Other | This is an environmental intervention consisting of a low-cost box fan with a sham filter (MERV 1) placed behind it. The company Lasko makes these fans and other environmental appliances. |
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This is an item on the ACQ. See primary outcome.
| ACQ will be measured weekly for 6 consecutive weeks, two pre-intervention weeks (before box fans have been given to participant) and four weeks while fans are being used in the home. Symptoms will also be assessed at the six month follow-up visit. |
| Health care utilization in the past month | Will be assessed with the six-item asthma-related health care utilization questionnaire. | Will be evaluated at baseline (visit 1), after 6 weeks (visit 3) and at 6 month follow up (visit 4) |