Rapid Diagnosis of Severe Respiratory Tract Infectious Diseases and Screening of Biomarkers for Stratified Diagnosis

Rapid Diagnosis of Severe Respiratory Tract Infectious Diseases and Screening of Biomarkers for Stratified Diagnosis

The purpose of this study is to clarify the biomarkers for rapid diagnosis and stratified diagnosis of severe respiratory tract infectious diseases through clinical experiments.

Methods: The relationship between relevant biomarkers and stratified diagnosis was analyzed by collecting laboratory and etiological examinations of patients with severe pneumonia.

Inclusion Criteria:

• Meets the diagnostic criteria for severe pneumonia；
• Age≥18 years old and < 80 years old；
• Willing to sign informed consent for the course of the study；

Exclusion Criteria:

• Patients with intracranial hypertension, acute coronary syndrome, pleural fistula, pneumothorax, or subcutaneous emphysema;
• Pregnant and lactating patients;
• Severely hemodynamically unstable (an increase in vasopressors by more than 30% in the first 6 hours, or norepinephrine >0.5mg/kg/min);
• Those who do not consent to participate in this study；