Retrospective Study of Invasive Fungal Infections With Filamentous Fungi in Heart Transplant Patients

Multicenter Retrospective Cohort Study on Invasive Fungal Infections With Filamentous Fungi in Heart Transplant Patients

Invasive filamentous fungal infections (aspergillosis, scedosporiosis, mucormycosis, fusarium wilt) are common and serious in immunocompromised subjects and particularly organ transplant patients. There is little recent data in heart transplantation, particularly on the incidence and risk factors of fungal infections. . It is therefore important to have recent data on incidence, risk and prognostic factors in order to improve the management of this severe complication.

Inclusion Criteria:

• Adult patient ≥18 years old

• Heart transplant

• Invasive fungal infection with filamentous fungi during the period from January 1, 2008 to December 31, 2022

• Proven or probable infection with filamentous fungi according to EORTC/MSGERC criteria (20):

  • Invasive aspergillosis
  • Mucormycosis
  • Fusarium wilt
  • Scedosporiosis
  • Other filamentous fungus infection

• Subject who has not expressed, after information, his opposition to the reuse of his data for the purposes of this research.

Exclusion Criteria:

• Patient having expressed his opposition to participating in the study
• Patient not having a liver transplant
• Subject under guardianship, curatorship or safeguard of justice.