Minimal Clinically Important Difference of the Box and Block Test in Parkinson

Examining the Clinical Significance of the Change in Manual Dexterity of Parkinson's Patients Receiving Conventional Physiotherapy

The aim of this study is to examine the level of clinical change in gross manual skills of Parkinson's patients who receive conventional physiotherapy. For this purpose, the Box-Block Test will be used, and the amount of change that must occur in the patient's hand functions will be determined for the test to be considered clinically meaningful.

Patients will continue their routine physical therapy sessions and the researchers will not interfere with this program. The treatment program will be created by the clinical specialist physician and physiotherapist.

Upper extremity rehabilitation programs for Parkinson's patients generally consist of methods such as stretching, strengthening, reaching, coordination and recreational activities. Patients will receive physiotherapy for 30 sessions.

Inclusion Criteria:

• Being Hoehn & Yahr Stage between 1-3,
• Individuals in the "On" phase,
• Those who were not exposed to any physiotherapy intervention during the initial assessment

Exclusion Criteria:

• Mini-mental status assessment < 24 points;
• Presence of severe dyskinesia,
• Those who experience fluctuations in the on-off phase,
• Those who have undergone stereotaxic brain surgery for Parkinson's,
• Individuals with changes in dopamine dose within three months,
• Presence of unstable cardiac and respiratory disease
• Those with an orthopedic problem or a history of surgery affecting upper extremity performance.