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The aim was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects.
In lateral decubitus, the largest percentage of pulmonary ventilation of non-sedated subjects is distributed mainly in the dependent lung. The aim It was to investigate via impedance tomography apparatus the distribution of pulmonary ventilation at a lateral position at different Continuous Positive Airway Pressure levels (0, 5, 10 cm Η2Ο) in healthy subjects. The volunteers were noninvasively ventilated in both lateral positions and supine positions at the beginning and end of the process. It is concluded that implementing Non-Invasive Ventilation in the lateral body position resulted in increased ventilation of the dependent lung. In contrast, the respective ventilation of the non-dependent lung was further decreased.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Supine position | Active Comparator | Supine experimental position |
|
| Right position | Active Comparator | Right lateral decubitus |
|
| Left position | Active Comparator | Left lateral decubitus |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Positive End Expiratory Pressure 5 H2O | Device | Positive End Expiratory Pressure 5 H2O from CPAP apparatus |
|
| Measure | Description | Time Frame |
|---|---|---|
| The percentage change in pulmonary ventilation | The percentage change in pulmonary ventilation was measured at each position, without applying external positive end-expiratory pressure and under positive end-expiratory pressure of 5 and 10 cmH2O | Up to 3 minutes |
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Inclusion Criteria:
• Healthy Volunteers
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Konstantinos Grigoriadis, Dr | PT, Attikon University Hospital | Principal Investigator |
| Anna Grigoriadou, MSc | PT, Attikon University Hospital | Study Director |
| Frantzeska Frantzeskaki | MD, Attikon University Hospital | Study Director |
| Ioannis Efstathiou | PT, Attikon University Hospital | Study Director |
| Iraklis Tsangaris | Professor, Attikon University Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Attikon University Hospital | Athens | Attica | 12462 | Greece | ||
| Grigoriadis Konstantinos |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22872368 | Background | Schnidrig S, Casaulta C, Schibler A, Riedel T. Influence of end-expiratory level and tidal volume on gravitational ventilation distribution during tidal breathing in healthy adults. Eur J Appl Physiol. 2013 Mar;113(3):591-8. doi: 10.1007/s00421-012-2469-7. Epub 2012 Aug 8. | |
| 26933321 | Background | Sharma JP, Salhotra R, Kumar S, Tyagi A, Sethi AK. Noninvasive lung recruitment maneuver prevents reintubation and reduces ICU stay. Lung India. 2016 Jan-Feb;33(1):99-101. doi: 10.4103/0970-2113.173070. No abstract available. |
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The regional distribution of pulmonary ventilation was measured in the supine, right, and left lateral positions while alternating the sides to ensure randomization.
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| Positive End Expiratory Pressure 10 H2O | Device | Positive End Expiratory Pressure 5 H2O from CPAP apparatus |
|
| Athens |
| Attica |
| 18452 |
| Greece |
| 4055566 | Result | Hurewitz AN, Susskind H, Harold WH. Obesity alters regional ventilation in lateral decubitus position. J Appl Physiol (1985). 1985 Sep;59(3):774-83. doi: 10.1152/jappl.1985.59.3.774. |
| 29430443 | Result | Lobo B, Hermosa C, Abella A, Gordo F. Electrical impedance tomography. Ann Transl Med. 2018 Jan;6(2):26. doi: 10.21037/atm.2017.12.06. |
| 29945735 | Result | Miura MC, Ribeiro de Carvalho CR, Yamada da Silveira LT, de Moraes Regenga M, Petri Damiani L, Fu C. The effects of recruitment maneuver during noninvasive ventilation after coronary bypass grafting: A randomized trial. J Thorac Cardiovasc Surg. 2018 Dec;156(6):2170-2177.e1. doi: 10.1016/j.jtcvs.2018.05.004. Epub 2018 May 28. |
| 32086337 | Result | Nishimura M. Electrical Impedance Tomography: The Promise of Noninvasive Lung Images at the Bedside. Respir Care. 2020 Mar;65(3):402-403. doi: 10.4187/respcare.07716. No abstract available. |