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The goal of this observational study is to evaluate the efficacy and long-term clinical outcomes of early-stage lung cancer patients who have received surgery using the real-world data. The main questions it aims to answer are:
This observational study aims to comprehensively evaluate the effectiveness and long-term clinical outcomes of surgical interventions in early-stage lung cancer patients, utilizing real-world data.
Central to this investigation are two key questions:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sublobar resection group | Patients in this group have received Sublobar resection. |
| |
| Lobectomy group | Patients in this group have received lobectomy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sublobar resection | Other | Sublobar resection is a series of surgical approaches for lung cancer. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Disease-free survival(DFS) | Defined as the time from the date of randomization until the date of disease recurrence or death (by any cause in the absence of recurrence). | Defined as the time from the date of surgery until the date of first documented progression or death (by any cause in the absence of recurrence), whichever came first, assessed up to 10 years. |
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival (OS) | OS is defined as the time from surgery time until death from any cause. | From date of diagnosis until the date of death from any cause, whichever came first, assessed up to 10 years. |
| 5-year Overall Survival (overall survival) Rate |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with lung cancer who have received surgery.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Shugeng Gao, MD | Contact | 8610-87788177 | gaoshugeng@cicams.ac.cn |
| Name | Affiliation | Role |
|---|---|---|
| Shugeng Gao, MD | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shugeng Gao | Recruiting | Beijing | Beijing Municipality | 100020 | China |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D038481 | Anterior Temporal Lobectomy |
| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
| D019635 | Neurosurgical Procedures |
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| Lobectomy | Other | Lobectomy is the surgical approach for lung cancer. |
|
The time from surgery time until death from any cause, estimated from a Kaplan Meier plot of OS at the time of the primary analysis. |
| From date of surgery until date of death due to any cause. Assessed at 5 years. |
| Patterns of Relapse | Relapse was defined as disease recurrence at any site. | Within 10 years after surgery |
| Perioperative Complication rate | Complications after the surgery | Within 6 months after surgery |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |