Efficacy of Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen After Cesarean Section

Efficacy of Intravenous Acetaminophen Alone Versus Combination of Acetaminophen/Ibuprofen (Maxigesic®IV) in Multimodal Analgesia After Cesarean Section: a Randomized Controlled Trial

The investigators aim to compare the analgesic efficacy of intravenous acetaminophen alone versus combination of acetaminophen/ibuprofen (Maxigesic®IV) in multimodal analgesia after cesarean section.

Inclusion Criteria:

• Patients scheduled for elective cesarean section
• Gestational age > 37+0 weeks

Exclusion Criteria:

• Emergency cesarean section
• Multiple pregnancy (e.g. twins, triplets)
• Body weight < 50 kg
• Preeclampsia
• History of hypersensitivity to acetaminophen or ibuprofen
• History of upper gastrointestinal tract bleeding or gastric ulcer
• Underlying liver disease
• Underlying kidney disease or GFR < 90 mL/min/1.73m2
• Heart failure or severe hypertension
• History of asthma
• Chronic use of barbital or tricyclic antidepressants