Identification of Pattern and Factors Affecting Recurrenc... | NCT06465030

Studies
Identification of Pattern and Factors Affecting Recurrence in Head and Neck Carcinoma

NCT06465030

Sponsor

Sohag University

Status

Unknown status

Last Update Posted

Jun 25, 2024Actual

Enrollment

35Estimated

Phase

Not provided

Conditions

Recurrent Head and Neck Squamous Cell Carcinoma

Interventions

Not provided

Countries

Egypt

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

Annotation Module

Unposted Annotation

Unposted Responsible Party

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

May 2024

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jul 15, 2024Estimated

Primary Completion Date

Apr 2025Estimated

Completion Date

Jun 2025Estimated

First Submitted Date

May 29, 2024

First Submission Date that Met QC Criteria

Jun 16, 2024

First Posted Date

Jun 18, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Jun 21, 2024

Last Update Posted Date

Jun 25, 2024Actual

Description Module

Brief Summary

The study will evaluate the local experiences in treatment of head and neck carcinoma by retrospectively analyzing the incidence and location of recurrence, and also studying factors affecting this recurrence.

Detailed Description

The investigators will evaluate the local experience in treatment of head and neck SCC by retrospectively analyzing the incidence and location of recurrence, either; local recurrence (LR), regional recurrence (RR), or distant mets in eligible head and neck cancer patients treated with IMRT and VMAT in the period from 2018 till 2022 to allow a follow-up for at least 1 year.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

35Estimated

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Pattern of relapse in recurrent head and neck squamous cell carcinoma, evident clinically and measured by images "US,CT, MRI and endoscopy".	Local, locoregional recurrence by MRI neck and CT Neck and distant recurrence by pan CTs.	At least obsevation of 1 year FU of the patient

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Adults aged more than 18 years. Patients with primary non nasopharyngeal head and neck squamous cell carcinoma. Patients who were intended to receive radical treatment delivered by IMRT and VMAT techniques.

Exclusion Criteria:

Adults who had double malignancies. Metastatic HNSCC cases.

Accepts Healthy Volunteers

Not provided

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

Not provided

Standard Ages

AdultOlder Adult

Study Population

Patients with recurrent head and neck cancer after radical treatment by IMRT and VMAT, in Sohag city.

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Reem Gamal, M.B.B.Ch	Contact	01094086660		reemgamal4996@gmail.com

Overall Officials

Name	Affiliation	Role
Reem Gamal, M.B.B.Ch	Sohag university hospital, oncology and nuclear medicine department	Principal Investigator

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Sohag Faculty of Medicine	Recruiting	Sohag			Egypt

Type	Date	Date Unknown
Release	Dec 7, 2025
Reset	Dec 22, 2025

Submission Tracking

Estimated Results First Submitted Date

Dec 7, 2025

First MCP Posted Date

Not provided

Submission Infos

Release Date	Unrelease Date	Unrelease Date Unknown	Reset Date	MCP Release Number
Dec 7, 2025			Dec 22, 2025

Condition Browse Module

MeSH Terms

ID	Term
D000077195	Squamous Cell Carcinoma of Head and Neck

Ancestor Terms

ID	Term
D002294	Carcinoma, Squamous Cell
D002277	Carcinoma
D009375	Neoplasms, Glandular and Epithelial
D009370	Neoplasms by Histologic Type

Browse Leaves

Not provided

Browse Branches

Not provided