Reduced Carbohydrates + Ketogenic Supplement on Energy Metabolism

Effect of a Reduced Carbohydrates Menu Combined With a Ketogenic Supplement on Energy Metabolism in a Senior Residence: the SAGE-2 Study

The present study will evaluate the effects on glucose, ketones and other blood biomarkers, cognition, quality of life, physical activity and well-being of a reduced carbohydrate diet paired with a ketogenic product for 2 months in a population living in a senior residence. This study follows the KetoHome (fall 2022) and SAGE (fall 2023) projects which assessed the feasibility, acceptability and effectiveness of a reduced carbohydrate intervention alone.

Inclusion Criteria:

• Older men or women in a senior residence;
• Understand, read and write French;
• Have sufficient visual and hearing acuity to pass cognitive tests;
• Available during the intervention period

Exclusion Criteria:

• Body mass index < 20;
• T1 diabetic;
• T2 insulin-dependent diabetic;
• MMSE < 20;
• Weight loss >10% in the last 6 months involuntary or voluntary;
• Known and uncontrolled hypoglycemia;
• Moderate to severe digestive illnesses that can be aggravated by dietary changes;
• Severe dysphagia;
• Supplementation with MCT oil, ketone salts, ketone esters, adherence to the ketogenic diet, reduced carbohydrate diet, intermittent fasting or other diet or supplements that can significantly increase ketones in the last month;
• Participation in other interventional research projects on nutrition or aimed at metabolic change simultaneously.
• Medical condition that could prevent the participant from completing the study in the opinion of the doctor