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This study aimed to evaluate the effect of growth hormone, EndoSeal MTA sealer, and their combination on Healing of Periapical Pathosis.
Out of 100 healthy male patients aged 18 to 40 years, 32 were selected from outpatients attending the Endodontic Clinic of the Faculty of Dental Medicine, Al-Azhar University, Cairo, Egypt, to be included in this study. The selected patients have no medical contraindications for oral surgical procedures (Scores 1-2) according to the classification of the American Society of Anesthesiologists (ASA)(8). Single-rooted permanent teeth were selected according to specific inclusion criteria based on preoperative assessment of the patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Growth hormone group | Experimental | Teeth undergo Growth Hormone application before obturation using EndoSeal MTA sealer |
|
| Control group | Experimental | Teeth undergo conventional root canal obturation using EndoSeal MTA sealer without any additional intervention |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Growth hormone application | Procedure | Growth hormone application during non-surgical root canal treatment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Post operative CBCT scan | Evaluation of non surgical root canal tratment healing according to CBCTPAI | 6 months |
| Post operative CBCT scan | Evaluation of non surgical root canal tratment healing according to CBCTPAI | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Post operative pain assesment | The postoperative pain assessment was done after obturation, using the modified verbal descriptor scale (VDS) as follow The VDS consist of a scoring system translated into an Arabic, describes a list of adjectives describing the different level of pain including, no pain (score 0 -1), mild pain (score 2-3), moderate pain (score 4 -5), strong pain (score 6 - 7), severe pain (score 8 - 9), worst pain (score 10). |
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Inclusion Criteria:- Necrotic teeth with apical periodontitis.
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Al Azhar University | Cairo | Nasr City | 4450113 | Egypt |
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| Root canal treatment | Procedure | Teeth undergo conventional root canal treatment without any additional intervention |
|
| 6 hours |
| Post operative pain assesment | The postoperative pain assessment was done after obturation, using the modified verbal descriptor scale (VDS) as follow The VDS consist of a scoring system translated into an Arabic, describes a list of adjectives describing the different level of pain including, no pain (score 0 -1), mild pain (score 2-3), moderate pain (score 4 -5), strong pain (score 6 - 7), severe pain (score 8 - 9), worst pain (score 10). | 24 hours |
| Post operative pain assesment | The postoperative pain assessment was done after obturation, using the modified verbal descriptor scale (VDS) as follow The VDS consist of a scoring system translated into an Arabic, describes a list of adjectives describing the different level of pain including, no pain (score 0 -1), mild pain (score 2-3), moderate pain (score 4 -5), strong pain (score 6 - 7), severe pain (score 8 - 9), worst pain (score 10). | 48 hours |
| Post operative pain assesment | The postoperative pain assessment was done after obturation, using the modified verbal descriptor scale (VDS) as follow The VDS consist of a scoring system translated into an Arabic, describes a list of adjectives describing the different level of pain including, no pain (score 0 -1), mild pain (score 2-3), moderate pain (score 4 -5), strong pain (score 6 - 7), severe pain (score 8 - 9), worst pain (score 10). | 72 hours |
| Post operative pain assesment | The postoperative pain assessment was done after obturation, using the modified verbal descriptor scale (VDS) as follow The VDS consist of a scoring system translated into an Arabic, describes a list of adjectives describing the different level of pain including, no pain (score 0 -1), mild pain (score 2-3), moderate pain (score 4 -5), strong pain (score 6 - 7), severe pain (score 8 - 9), worst pain (score 10). | 1 week |