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In this study the investigators aim to study the effect of supplementation of CoQ10 in decreasing the incidence of contrast induced acute kidney injury in patients with acute coronary syndrome undergoing coronary angiography.
Patients who fulfilled the inclusion criteria and agreed to participate in the study will be randomly divided into 2 groups using their computer generated random numbers that group a will receive the coenzyme Q10 in addition to the standard preventive measures and group b will receive only the standard preventive measures without the coenzyme Q10.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Coenzyme Q10 100 Milligrams Oral Capsule | Experimental | Coenzyme Group received coenzyme Q10 in addition to the the standard preventive measures |
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| Placebo group | Placebo Comparator | Placebo Group received only the standard preventive measures |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coenzyme Q10 100 Milligrams Oral Capsule | Drug | Patients will be randomly divided into two groups using a computer generated random number chart Coenzyme Q10 group will receive 400 milligrams coenzyme Q10 preoperative and 400 milligrams coenzyme Q10 for 3 days post operative in addition to the standard preventive measures. |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of the Creatinine rise in 1st 48-72 hours in ccu | a rise in serum creatinine of at least 0.5 mg/dL or a 25% increase from baseline within 48 to 72 hours after contrast exposure | 48-72 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ramy Mohamed, Resident | Contact | 01002820102 | 96ramymohamed22@gmail.com | |
| Ramy Mohamed mostafa, Resident | Contact | 01002820102 | 96ramymohamed22@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| RAMY Mohamed | Resident of cardiology department,Ain shams university | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain Shams university hospitals | Recruiting | Cairo | Egypt |
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| ID | Term |
|---|---|
| C024989 | coenzyme Q10 |
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| Placebo | Drug | placebo group will receive only the standard preventive measures (as proper hydration pre and post operative)without the coenzyme Q10. |
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| Ramy Mohamed Mostafa | Not yet recruiting | Cairo | Egypt |
|