Second Primary Cancer and Early-onset Colorectal Cancer

Risk Factors, Cancer Types and Prognostic Significance of Second Primary Cancer Based on the Early-onset and Late-onset Colorectal Cancer

The objective of this study was to analyze the pathological factors influencing the occurrence and prognosis of SPC in CRC patients of varying ages and compare the differences in the patterns of SPC occurrence and prognosis among patients of different age groups.

Inclusion Criteria:

• Patients undergoing radical surgery for colorectal cancer at Fudan University Shanghai Cancer Center between January 2008 and December 2018.
• Stage Ⅰ-Ⅳ colorectal cancer confirmed by clear pathological information

Exclusion Criteria:

• Previous history of other cancers before surgery
• Patients under 18 years old or over 80 years old