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This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.
Specifically, investigator want to investigate the effect of having a diagnosis of CRC before the age of 35 years on:disease stage at presentation, insurance status at diagnosis, treatment patterns by stage, and adjusted cancer-specific survival. The hypothesis is that patients younger than 35 years of age with CRC will present with more advanced disease at diagnosis but will have longer survival overall through more aggressive therapy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| colorectal cancer (CRC) patients younger than 35 | The hypothesis is that patients younger than 35 years of age with CRC will present with more advanced disease at diagnosis but will have longer survival overall through more aggressive therapy. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Colorectal cancer | Other | CRC is a disease that is often associated with older adults (<50 years). CRC remains the second most common cause of cancer death in males and the third most common cancer death in women. Despite this, CRC incidence has steadily declined in older adults; however, there is a concerning rise of incidence of colorectal cancer in young patients. The incidence of CRC in men and women under the age of 50 steadily increased 2.1 percent per year from 1992 through 2012. |
| Measure | Description | Time Frame |
|---|---|---|
| Age | colorectal cancer (CRC) patients younger than 35 years and comparing them against CRC patients older than 35 years of age. | 20 years |
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Inclusion Criteria:
Exclusion Criteria:
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This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Crystee Cooper, DHEd | Contact | 214-947-1280 | ClinicalResearch@mhd.com | |
| Kavya Mankulangara | Contact | 214-947-4604 | ClinicalResearch@mhd.com |
| Name | Affiliation | Role |
|---|---|---|
| Rohan Jeyarajah, MD | Methodist Health System | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Methodist Dallas Medical Center- Clinical Research Institute | Recruiting | Dallas | Texas | 75203 | United States |
The data attained will be de-identified prior to sharing via presentation and/or publication in relevant research mediums.
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |