Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

The purpose of this study is to examine hypoxic vasodilation and the role of beta-adrenergic receptors in younger premenopausal, perimenopausal, and older postmenopausal women.

Inclusion Criteria:

• Female assigned at birth
• Pre, peri- or post-menopausal
• Healthy weight (BMI ≥18 and ≤30 kg/m2)

Exclusion Criteria:

• Male (assigned at birth)
• Pregnancy, breastfeeding
• Use of hormone replacement therapies
• Hysterectomy
• Body mass index >30 kg/m2
• Diagnosed sleep apnea
• Current smoking/Nicotine/Drug use
• Nerve/neurologic disease
• Cardiovascular, hepatic, renal, respiratory disease
• Blood pressure ≥140/90 mmHg
• Diabetes, Polycystic ovarian syndrome
• Communication barriers
• Prescription medications
• Malignant cancer