Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo

Assessment of Hypoxia Inducible Factor and Autophagy Related Genes in Patients With Non-Segmental Vitiligo

The present study will aim to evaluate:

1. The presence of Hypoxia Inducible Factor in vitiligo patient
2. Defect of Autophagy Related Genes in vitiligo patient
3. The cross relation between Autophagy Related Genes and Hypoxia Inducible Factor in the pathogenesis of vitiligo among Egyptian patients in Sohag Governorate

Inclusion Criteria:

• Adult >18 years
• With non segmental vitiligo
• A group of participants will be included as a control group

Exclusion Criteria:

• Pregnancy
• Patient with chronic inflammatory skin disorders
• patient on anti-oxidant or anti-inflammatory drugs
• patient on topical or systemic treatment for vitiligo in last 4 weeks
• patients with other autoimmune diseases
• patients with diabetes mellitus