Expression of LC3-I, LC3-II & Beclin 1 in Vitiligo

Expression of LC3-I, LC3-II & Beclin 1 in Vitiligo and Healthy Control; Comparative Study

The exact mechanism of impairment of autophagy in vitiligo has not yet been determined.

Inclusion Criteria:

• • Patients with non-segmental vitiligo whether active or stable.

  • Age above 12 years.
  • Both sexes.

Exclusion Criteria:

• • Patients should not use any topical or systemic treatment at least 6 weeks before inclusion into the study.

  • Patients having other autoimmune disease, heart disease, liver disease, kidney disease, neurological disorder, cancer, active infection or any chronic disease.
  • Pregnancy or breast feeding for female patients.