The Relationship Between Microbiota and Coronary Ectasia

The Evaluation of the Relationship Between Coronary Ectasia And Trimethylamine N Oxide

Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ. In addition, the microbiota, through its metabolites, is involved in the pathophysiology or progression of a wide range of diseases, from atherosclerotic diseases to metabolic diseases and even neurological diseases. Among these metabolites, trimethylamine n-oxide metabolite has been shown to be particularly effective on atherosclerotic heart diseases.

Inclusion Criteria:

• over 18 years old
• not having occlusive coronary artery disease
• having coronary ectasia

Exclusion Criteria:

• patients with chronic kidney disease,
• revascularized coronary artery disease,
• previously documented critical coronary stenosis,
• acute or chronic inflammatory disease,
• rheumatologic disease,
• known active malignant disease,
• heart failure,
• moderate-to-severe valvular pathology
• patients who were on any steroid or immunosuppressive therapy