Comparison of Postoperative Analgesia Methods in Patients Undergoing Major Intraabdominal Surgery

Comparison of Postoperative Analgesia Methods in Patients Undergoing Major Intraabdominal Surgery

This study aims to examine the effects of M-TAPA applied for postoperative analgesia in patients who had major intraabdominal surgery on the postoperative pain score, the change in the postoperative total opioid requirement and the side effects.

The investigators seperated the patients into two groups as M-TAPA applied group and control group.In group M-TAPA, M-TAPA block was performed bilaterally with 20 mL of 0.2% bupivacaine under ultrasound guidance at the end of surgery. No block was performed in the control group. The participants were administered morphine through patient controlled analgesia (PCA) pump with a bolus dose of 1 mg, 15 min lockout interval. The postoperative pain scores (the numeric rating scores (NRS)), total opiod consumption in the first 48 h, and opioid related side effects were recorded.

Inclusion Criteria:

• patient > 17 years old
• ASA score 1-3
• undergoing major intra-abdominal surgery

Exclusion Criteria:

• ASA IV patients
• patients with known neurological or psychiatric disorders
• patients with clinically significant cardiovascular, respiratory, hepatic, renal or metabolic disease
• patients with long-term drug (opioid) or alcohol dependence
• patients with BMI>30
• patients with intellectual disability
• patients who developed massive bleeding and coagulopathy