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A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis.
60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise).
Measurements are taken before and after initial periodontal treatment in the periodontal subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MINST non surgical periodontal treatment | Experimental | Periodontitis patients treated by means of MINST. Patients were treated with non-surgical MINST periodontal treatment in a single session. |
|
| Q-SI non surgical periodontal treatment | Active Comparator | Periodontitis patients treated by means of Q-SI. Patients were treated with non-surgical quadrantwise periodontal treatment in 4 sessions, 1 session per week. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probin Pocket Depth reduction | Other | Probin Pocket Depth reduction in millimetres before and after treatment |
|
| Measure | Description | Time Frame |
|---|---|---|
| Probing Pocket Depth | Reduction in Probing Pocket Depth after treatnebt | 6-months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Gaetano Isola | Contact | 0953785652 | gaetano.isola@unict.it | |
| Rosalia Leonardi | Contact | 0953785652 | rleonardi@unict.it |
| Name | Affiliation | Role |
|---|---|---|
| Gaetano Isola | Università degli Studi di Catania | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| AOU Policlinico G. Rodolico | Recruiting | Catania | 95124 | Italy |
Study results
1-year
Pubmed
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| ID | Term |
|---|---|
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
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Non-surgical periodontal treatment Subgingival biofilm ultrasonic debridement with MINST or Q-SI
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Sealed envelopes