Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.

Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis: a Randomized-controlled Clinical Trial.

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with periodontitis and without any cardiovascular disease.

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment on endothelial dysfunction parameters in subjects with periodontitis.

44 patients with periodontitis treated with non surgical approach through Quadrant subgingival debridement or MINST.

All the patients are assessed for clinical, periodontal, blood and non-invasive ultrasound cardiovascular parameters. Measurements are taken before and after initial periodontal treatment in the periodontal subjects.

PERIODONTITIS GROUP

Inclusion Criteria:

• Clinically diagnosed with periodontitis according to the EFP/AAP 2017 criteria.

Exclusion Criteria:

• Periodontal treatment, antibiotics, NSAIDs, immunosuppressants during the last 6 months.
• Pregnancy.
• Cardiovascular Diseases.