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The aim of this study is to compare the effectiveness of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia in gynecological cancer surgeries.
The key question(s) it aims to answer are:
[Is intrathecal morphine more effective in postoperative analgesia?] Patients who underwent gynecological cancer surgery were examined retrospectively. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block applied for postoperative analgesia on pain scores and postoperative opioid use.
Our study was designed retrospectively. The investigators evaluated analgesia methods in patients who underwent laparoscopic or open surgery due to gynecological cancer between June 2023 and December 2023. The investigators evaluated the effect of intrathecal morphine and four-quadrant transversus abdominis plane block on postoperative analgesia and opioid use.
Group 1: Intrathecal morphine administered group Group 2: Four quadrant transversus abdominis plane block applied group
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1: Intrathecal morphine administered group | Group 1: Intrathecal morphine administered group |
| |
| Group 2: Four quadrant transversus abdominis plane block applied group | Group 2: Four quadrant transversus abdominis plane block applied group |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intrathecal morphine administered group, Four quadrant transversus abdominis plane block applied group | Procedure | Intrathecal morphine administered group and Four quadrant transversus abdominis plane block applied group |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative numerical rating scale | Our primary aim was to evaluate numerical rating scale at 24 hours postoperatively. numerical rating scale(NRS) was used to assess postoperative pain. NRS values were recorded For example, 0-10 where 0 is no pain and 10 is the worst pain imaginable. | 24 hours postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| postoperative opioid use | Our secondary aim was to evaluate opioid demand and consumption amounts in the postoperative 24 hours. | 24 hours postoperatively |
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Inclusion Criteria:
18 years
Exclusion Criteria:
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Between June 1, 2023 and December 1, 2023, 71 patients over the age of 18 who underwent surgery for ASA II and III gynecological cancer, to whom we applied intrathecal morphine or four-quadrant transversus abdominis plane block (TAPB) from peripheral nerve blocks for postoperative analgesia, were included in the study.
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| Name | Affiliation | Role |
|---|---|---|
| Duygu Akyol | Başakşehir Çam & Sakura City Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Başakşehir Çam and Sakura City Hospital | Istanbul | Basaksehir | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37729808 | Result | Black KA, Nelson G, Goucher N, Foley J, Pin S, Chong M, Ghosh S, Bisch SP. Effect of transversus abdominis plane block on postoperative outcomes in gynecologic oncology patients managed on an Enhanced Recovery After Surgery pathway. Gynecol Oncol. 2023 Nov;178:1-7. doi: 10.1016/j.ygyno.2023.09.003. Epub 2023 Sep 18. | |
| 26319886 | Result |
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| Niraj G, Kelkar A, Hart E, Kaushik V, Fleet D, Jameson J. Four quadrant transversus abdominis plane block and continuous transversus abdominis plane analgesia: a 3-year prospective audit in 124 patients. J Clin Anesth. 2015 Nov;27(7):579-84. doi: 10.1016/j.jclinane.2015.07.005. Epub 2015 Aug 28. |
| 35803751 | Result | Pirie K, Traer E, Finniss D, Myles PS, Riedel B. Current approaches to acute postoperative pain management after major abdominal surgery: a narrative review and future directions. Br J Anaesth. 2022 Sep;129(3):378-393. doi: 10.1016/j.bja.2022.05.029. Epub 2022 Jul 6. |
| 19151046 | Result | Meylan N, Elia N, Lysakowski C, Tramer MR. Benefit and risk of intrathecal morphine without local anaesthetic in patients undergoing major surgery: meta-analysis of randomized trials. Br J Anaesth. 2009 Feb;102(2):156-67. doi: 10.1093/bja/aen368. |