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| Name | Class |
|---|---|
| Centre de Recherche en Nutrition Humaine d'Auvergne | OTHER_GOV |
| Université d'Auvergne | OTHER |
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The aim of this study done in healthy, non-malnourished young and elderly subjects, is to measure the bioavailability of protein intake and the variation of metabolic markers following consumption of pea protein " NUTRALYS ® S85 plus" or a reference protein brought in water either alone or at the end of a standardized meal.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Young volunteers | Other | Volunteers under 30 years old |
|
| Elderly volunteers | Other | Volunteers over 65 years old. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pea protein (NUTRALYS ® S85 plus) in water | Dietary Supplement | After selection and randomization, the subjects will consume per os Pea protein (NUTRALYS® S85 plus) in water containing 0,41 g of tested protein/kg of body weight. |
| Measure | Description | Time Frame |
|---|---|---|
| Leucine blood concentration | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. |
| Measure | Description | Time Frame |
|---|---|---|
| Essential amino acids blood concentration (µmol/L) | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. | |
| Non essential amino acid blood concentration (µmol/L) | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Unité d'Exploration en Nutrition Centre de Recherche en Nutrition Humaine d'Auvergne | Clermont-Ferrand | 63009 | France |
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| ID | Term |
|---|---|
| D000078724 | Pea Proteins |
| D000067816 | Whey Proteins |
| D014867 | Water |
| ID | Term |
|---|---|
| D014674 | Plant Proteins, Dietary |
| D004044 | Dietary Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
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| Pea protein (NUTRALYS ® S85 plus) within meal | Dietary Supplement | After selection and randomization, the subjects will consume per os Pea protein (NUTRALYS® S85 plus) within a meal containing 0,41 g of tested protein/kg of body weight. |
|
| Whey protein in water | Dietary Supplement | After selection and randomization, the subjects will consume per os whey protein in water containing 0,41 g of tested protein/kg of body weight. |
|
| Whey protein within meal | Dietary Supplement | After selection and randomization, the subjects will consume per os whey protein within a meal containing 0,41 g of tested protein/kg of body weight. |
|
| Blood glucose concentration (g/L) | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. |
| Blood insulin concentration (μIU/ml) | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. |
| Blood lipid profile (glycerol concentration in mg/l and non-esterified fatty acids concentration in mg/l) | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. |
| Blood inflammatory profile (TNF-α blood concentration in pg/ml and IL-6 blood concentration in pg/ml) | 0 minute before eating the test meals, then regularly until 360 minutes after ingestion. |
| D010940 |
| Plant Proteins |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
| D008894 | Milk Proteins |
| D000080224 | Animal Proteins, Dietary |
| D000067796 | Whey |
| D008892 | Milk |
| D003611 | Dairy Products |
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D000838 | Anions |
| D007477 | Ions |
| D004573 | Electrolytes |
| D010087 | Oxides |
| D017601 | Oxygen Compounds |