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Obesity and diabetes share a common insulin resistance pathway and contribute to chronic hyperglycemia. Both high-intensity interval exercise (HIIE) and focused ultrasound (FUS) have been explored in the context of managing insulin resistance in diabetic individuals with abdominal obesity, though they operate through different mechanisms and have different implications.
Forty diabetic females aged 25 to 35 years old and body mass index was ≥ 30 kg/m², will participate in this study. They will be assigned into two equal groups, Group A will receive high intensity interval exercise 2 times per week for 4 months in addition to intermitted fasting diet. Group B will receive focused ultrasound 2 times per week for 4 months in addition to intermitted fasting diet. Assessment of abdominal obesity will be applied pre and post treatment through measuring Body mass index (BMI), Waist circumference (WC) in addition to Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A High intrerval trainig exercise group | Experimental | Group A will receive high intensity interval exercise 2 times per week for 4 months in addition to intermitted fasting diet. |
|
| Group B Focused ultrasound group | Experimental | Group B will receive focused ultrasound 2 times per week for 4 months in addition to intermitted fasting diet. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High intensity interval exercise | Other | HIIT is a type of interval training exercise. It incorporates several rounds that alternate between several minutes of high intensity movements followed by short periods of lower intensity movements 2 times per week for 4 months. |
| Measure | Description | Time Frame |
|---|---|---|
| Body mass index | The weight and height of each woman in both groups will be measured to calculate the body mass index (BMI) | Before starting the study and after 4 months of treatment |
| Waist circumference | Assessment of waist circumference of each woman by the tape measurement | Before starting the study and after 4 months of treatment |
| Skin fold | The thickness of the abdominal fold will be measured using skinfold calipers to provide information on changes in subcutaneous fat in the abdominal region. | Before starting the study and after 4 months of treatment |
| Value of HbA1c and HOMA-IR hormone | Value of HbA1c and HOMA-IR hormone will be measured to determine effect of treatment on insulin resistance. | Before starting the study and after 4 months of treatment |
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Inclusion Criteria:
They will be recruited from El_shinnawy physical therapy Centre.
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zeezy Soliman Eraky, Lecturer | Contact | 01003934051 | zeezyeraky@gmail.com | |
| Noha Ahmed Fouad Abd El Rahman, Lecturer | Contact | 01287499364 | Noha.ahmedfouad@buc.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed M. Elshinnawy, Assistant | Horus University | Principal Investigator |
| Haitham M. Elmasry, Lecturer | MTI University | Principal Investigator |
| Shimaa hussien ahmed roshdy, Lecturer |
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| ID | Term |
|---|---|
| D007333 | Insulin Resistance |
| D056128 | Obesity, Abdominal |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D000072696 | High-Intensity Interval Training |
| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
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| Focused ultrasound | Other | Focused ultrasound will be applied over the anterior abdominal, two sessions per week for 4 months, each session 40 minutes. |
|
| Misr University for Science and Technology |
| Principal Investigator |
| D009765 | Obesity |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D004700 | Endocrine System Diseases |
| D009142 |
| Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |