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Healthy volunteers ages 25-40 from the general US population who meet the eligibility criteria and are enrolled will (a) play Lumosity games at least 20 times each in under 60 days and (b) then complete one session of task-based functional magnetic resonance imaging (fMRI) while playing Lumosity games.
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| Measure | Description | Time Frame |
|---|---|---|
| BOLD response during gameplay | Whole-brain blood oxygen level-dependent (BOLD) response during gameplay | Day 60 |
| Responder rates | Percentage of participants who show A) BOLD response by brain region during gameplay, B) Between-network connectivity, based on BOLD responses, during gameplay, C) Within-network connectivity, based on BOLD responses, during gameplay | Day 60 |
| Structural MRI volumetrics: Volume | Volume at rest | Day 60 |
| Structural MRI volumetrics: Cortical thickness | Cortical thickness measured in millimeters | Day 60 |
| Structural MRI volumetrics: Brain-Predicted Age Difference | Brain-Predicted Age Difference at rest | Day 60 |
| Behavior response: Game score | Score on game after completion of gameplay | Day 60 |
| BAMS-7 (Brief Attention and Mood Scale of 7 Items) | Subject-reported BAMS-7 (Brief Attention and Mood Scale of 7 Items) including the Attention subscale, Mood subscale, and Total, measured post-imaging | Day 60 |
| VGPQ (Video Game Playing Questionnaire) |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy adults age 25-40
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| Name | Affiliation | Role |
|---|---|---|
| Kevin Madore, PhD | Lumos Labs, Inc. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UC Davis Imaging Research Center (IRC) | Sacramento | California | 95817 | United States |
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Subject-reported VGPQ (Video Game Playing Questionnaire) including non-video game playing (NVGP) and video game playing (VGP)
| Day 60 |