Creatine and GAA for Brain Oxygenation

Enhancing Brain Oxygenation: Effects of Short-Term Co-Administration of Creatine and Guanidinoacetic Acid at Rest and During Stress

The main aim of this randomized controlled trial is to evaluate cerebral blood oxygenation after 7-day administration of a creatine-guanidinoacetic acid (GAA) mixture in healthy adults before, during, and after a series of cognitive tests.

Inclusion Criteria:

• Age 18-30 years
• Absence of metabolic disorders or other health complications
• Provision of signed informed consent

Exclusion Criteria:

• History of dietary supplement use within the preceding 4 weeks
• Lack of consent to randomization
• Concurrent participation in other studies