Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology

Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology

This study included patients who underwent surgical treatment for incisional hernia and non-hernia conditions. Surgical specimens were collected for transcriptome sequencing to obtain the gene expression list. Then genes analyzed by Gene Ontology, protein interactions, and signaling pathway enrichment using the expression matrix.

Inclusion Criteria:

1.18 to 75 years 2.diagnosed with incisional hernia 3.normal tumour markers 4.elective surgery patients.

Exclusion Criteria:

1. patients with vital organ failure (heart liver, lung, kidney and others)
2. malignant tumors not been completely relieved by active treatment,
3. patients who have psychiatric diseases or comprehension disorders.
4. patients with metabolic disease involving connective tissue collagen.