Application of tear ferning test for clinical dry eye diagnosis

Comparing dry eye patients' tear ferning structure with non-dry eye patients' to develop a protocol for easy and costless diagnosis in ophthalmology.

Inclusion Criteria:

• Aged between 20 and 65 years
• For dry eye disease group:
• Schirmer's test results between 5 - 10 mm
• Tear Film Break Up Time less than 10 seconds
• Ocular Surface Disease Index of more than 25

Exclusion Criteria:

• Those have diabetes, hypertension or other chronic diseases
• No evident ocular diseases such as cornea disease, cataracts, vitreous degeneration, glaucoma, and retinopathy.
• Belong to vulnerable groups(pregnancy woman, prisoner, ethical minorities, economic or educationally disadvantaged subjects, disabled individuals such as those at terminal stage of tumorigenesis, blindness, terminal ill individuals)