The aim of the current study is to assess the desensitising effect of nanosilver fluoride on first permanent molars (FPMs) in patients with MIH in comparison to low-level laser therapy.

Inclusion Criteria:

• The presence of at least one hypersensitive first permanent molar in MIH patient (using the Schiff Cold Air Sensitivity Scale (SCASS)).
• Completion of an informed consent to participate in the study.

Exclusion Criteria:

• Hypomineralised molars resulting from other medical conditions, such as enamel malformations associated with syndromes, dental fluorosis, enamel hypoplasia, amelogenesis imperfecta, and dental caries.
• The presence of active tooth decay or defective restorations in the tooth under examination which can confound the aetiology of hypersensitivity with pulpitis.
• The presence of pulpal symptoms.
• Having undergone any professional desensitising treatment in the previous 6 months.
• Having used a desensitising paste other than habitual toothpaste in the previous 3 months.
• Use of anti-inflammatory drugs or analgesics at the time of recruitment.
• Allergy or sensitivity to silver or any of the materials included in the study.