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This study was designed as a single-center, randomized, open, two-cycle, cross-over trial. It is planned to enroll 18 healthy subjects
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Treatment group A | Experimental | Take Herombopag Olamine Tablets 7.5mg 30min after high-fat meal in the first cycle. in the second cycle, take Herombopag Olamine Tablets 7.5mg on an empty stomach |
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| Treatment group B | Experimental | Take Herombopag Olamine Tablets 7.5mg 30min on an empty stomach in the first cycle. In the second cycle, take Herombopag Olamine Tablets 7.5mg 30min fter high-fat meal |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Herombopag Olamine Tablets | Drug | Three Herombopag Olamine Tablets is administered to healthy subjects. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Cmax | 0hour to 120hours after the last dosing | |
| AUC0-t | 0hour to 120hours after the last dosing | |
| AUC0-∞ | 0hour to 120hours after the last dosing |
| Measure | Description | Time Frame |
|---|---|---|
| Tmax | 0hour to 120hours after the last dosing | |
| t1/2 | 0hour to 120hours after the last dosing | |
| CL/F |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sheng Feng | Contact | +86-0518-82342973 | sheng.feng@hengrui.com | |
| Weijie Kong | Contact | +86-0518-82342973 | hongda.lin@hengrui.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The Second Hospital of Anhui Medical Uniersity | Hefei | Anhui | 230601 | China |
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| 0hour to 120hours after the last dosing |
| V/F | 0hour to 120hours after the last dosing |
| Incidence and severity of adverse events (AEs) | from screening to 120 hours after the last dosing |