Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut microbiome. The study team also wants to understand if adding potato starch to participant's diet helps these bacteria make more short chain fatty acids, a byproduct the team thinks may benefit participant's health.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Potato starch supplement | Experimental | Participants will take the supplement for approximately 4 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Potato Starch | Dietary Supplement | Participants will consume 10 grams (1/2 a packet) of Bob's Red Mill Potato Starch twice a day for the first 7 days and then increase to 20 grams (full packet) of potato starch for approximately 3 weeks. Potato starch can be mixed into cold food or beverage for consumption. In addition, participants will have evaluations and provide blood and stool samples during the study. |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in Short Chain Fatty Acid (SCFA) butyrate levels - stool | Stool will be analyzed. | Baseline, approximately 4 weeks |
| Changes in Short Chain Fatty Acid (SCFA) butyrate levels - plasma | Plasma samples will be analyzed. | Baseline, approximately 4 weeks |
| Changes in propionate levels - stool | Stool will be analyzed. | Baseline, approximately 4 weeks |
| Changes in propionate levels- plasma | Plasma samples will be analyzed. | Baseline, approximately 4 weeks |
| Changes in acetate levels- stool | Stool will be analyzed. | Baseline, approximately 4 weeks |
| Changes in acetate levels- plasma | Plasma samples will be analyzed. | Baseline, approximately 4 weeks |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hayley Billingsley, PhD | Contact | 734-726-0308 | hbilings@med.umich.edu |
| Name | Affiliation | Role |
|---|---|---|
| Scott Hummel, MD, MS | University of Michigan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Michigan | Recruiting | Ann Arbor | Michigan | 48109 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|