Brain Mechanisms of Reducing Polysubstance Use

Brain Mechanisms of Reducing Polysubstance Use Following a Novel Body-mind Intervention 2

The proposed study will test whether neurofeedback (NF) could optimize integrative body-mind training (IBMT) practice.

The proposed study will test whether real-time NF could optimize IBMT practice and improve effects in reducing polysubstance use through targeting self-control networks in the brain.

Inclusion Criteria:

• At least 18 years old
• Free of any psychiatric diagnoses or medication (besides a substance use disorder (SUD) to alcohol, tobacco, or cannabis)
• In the past month, at least 4 episodes of heavy episodic drinking; at least 3 occasions of cannabis use; and daily cigarette use for at least the past month
• Normal or corrected-to-normal vision
• Written informed consent
• No previous meditation or NF experiences

Exclusion Criteria:

• Any psychiatric diagnoses other than an SUD
• Medical disorder(s) that may affect the central nervous system; medications that affect the central and autonomic nervous system; or a positive pregnancy test result (females)
• Excluding cannabis, evidence of recent (past month) illicit drug use