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This study aimed to evaluate the effect of epidural patient-controlled analgesia (PCA) on postoperative pain relief after lumbar spine surgeries. The eligible patients received two types of postoperative pain management: PCA and standard pain treatment. Comparisons between the two groups were made in terms of postoperative pain level.
This study included patients who underwent lumbar spine surgeries for degenerative spinal disease. The eligible patients were divided into two groups, the PCA group and the control group, for two types of postoperative pain management. The patients in the PCA group received 72-hour epidural PCA. The PCA catheter was inserted by the surgeon prior to wound closure in the lumbar spine surgery. The PCA catheter was maintained until 72 hours after the surgery and was removed at the postoperative day 4. The control group received postoperative standard pain treatment, including oral acetaminophen and muscle relaxants. No non-steroidal anti-inflammatory drugs were given in this study. All patients were provided the option to request intramuscular morphine injection (0.5 mg of morphine) for additional pain control, with a minimum interval of 6 hours between doses. Pain assessment was conducted using a visual analogue scale on the first four postoperative days and on the day of discharge. At the postoperative day 4, pain assessment was performed before the PCA removal. The level of pain and the number of morphine injections were compared between the two groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PCA group | Patients received epidural patient-controlled analgesia for postoperative pain. |
| |
| Control group | Patients received standard of care for postoperative pain. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Epidural patient-controlled analgesia | Procedure | Epidural patient-controlled analgesia for postoperative pain after lumber spine surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain degree | Pain degree was assessed using a visual analogue scale the on the first four postoperative days and on the day of discharge. | Postoperative day 1, postoperative day 2, postoperative day 3, postoperative day 4, and the day of discharge (up to 1 month) |
| Measure | Description | Time Frame |
|---|---|---|
| The number of morphine injections | The number of intramuscular morphine injections for additional pain control with a minimum interval of 6 hours between doses. | The day of discharge (up to 1 month) |
| Measure | Description | Time Frame |
|---|---|---|
| Length of hospitalization | The length of hospital stay (day) | The day of discharge (up to 1 month) |
| Drainage amount | The amount of postoperative drainage (ml) |
Inclusion Criteria:
Exclusion Criteria:
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Patients who underwent lumbar spine surgeries at Taipei City Hospital
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| Name | Affiliation | Role |
|---|---|---|
| Hsin-chang Chen, MD | Taipei City Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Taipei City Hospital | Taipei | Taiwan |
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| Standard postoperative pain management | Procedure | Standard of care for postoperative pain after lumber spine surgery |
|
| The day of discharge (up to 1 month) |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009422 | Nervous System Diseases |