Intrathecal Dexmedetomidine vs Midazolame

Prospective Randomized Controlled Clinical Trial to Compare Intrathecal Dexmedetomidine Versus Midazolame in Orthopedic Cancer Surgeries

Prospective Randomized Controlled Clinical Trial to Compare Intrathecal Dexmedetomidine Versus Midazolame in Orthopedic Cancer Surgeries

Comparison of intrathecal dexmedetomidine plus Bupivacaine vs intrathecal midazolam plus Bupivacaine on duration of sensory and motor blockade and hemodynamic parameters of patients

Inclusion Criteria:

• Patients undergoing lower limb orthopedic cancer surgery.
• ASA I, II, III.
• Age 20 to 70 year
• Healthy volunteers

Exclusion Criteria:

• Age less than 20 and older than 70.
• ASA IV, V.
• patients' refusal.
• patients with coagulopathy.
• patients with severe valvular stenosis
• patients with infection at site of injection