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| Name | Class |
|---|---|
| BioActor | INDUSTRY |
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The main objective of this study is to study the bioavailability and kinetics of acute Aronia Melanocarpa supplementation in healthy young (18-35 years) and older adults (55-75 years) adults. During the test day, participants will ingest a drink consisting of Aronia Melanocarpa extract (AME). The bioavailability and kinetics of AME will be assessed via frequent blood sampling, urine collection, and faecal sampling, in which AME and metabolite profiles will be quantified.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Aronia Melanocarpa extract | Experimental | a drink consisting of AME (Aronia Melanocarpa extract) and water. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aronia Melanocarpa extract | Dietary Supplement | Aronia Melanocarpa extract (AME) consisting of a mixture of anthocyanins and other polyphenols |
|
| Measure | Description | Time Frame |
|---|---|---|
| Aronia metabolites in blood | Concentrations and quality of Aronia metabolites in blood analysed with LC-MS | time = 0 hours until t = 48 hours |
| Aronia metabolites in urine | Concentrations and quality of Aronia metabolites in urine analysed with LC-MS | time = 0 hours until t = 48 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Aronia metabolites in feces | Concentrations and quality of Aronia metabolites in feces analysed with LC-MS | time = 0 hours |
| length - baseline characteristics | length |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Sanne Ahles, Msc | Contact | +31437114555 | s.ahles@maastrichtuniversity.nl |
| Name | Affiliation | Role |
|---|---|---|
| Jogchum Plat, Prof | Maastricht University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maastricht University | Recruiting | Maastricht | Netherlands |
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| time = 0 hours |
| weight - baseline characteristics | weight | time = 0 hours |
| blood pressure (systolic and diastolic) - baseline characteristics | blood pressure | time = 0 hours |