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| Name | Class |
|---|---|
| BioActor B.V. | INDUSTRY |
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There is a great interest in improving cognitive performance, including memory and attention. Improved attention is desirable for a large group of people because it is linked to improved performance . Students and professionals can benefit from improved attention and thus performance in academic and other work environments. In addition, cognitive functioning also plays an important role in sports. Various cognitive skills, including attention, reaction time and motor function, have shown that they can influence sport performance. A completely natural supplement with aronia melanocarpa extract could be a promising way to naturally improve cognitive performance.
There is a great interest in improving cognitive performance, including memory and attention. Improved attention is desirable for a large group of people because it is linked to improved performance. Students and professionals can benefit from improved attention and thus performance in academic and other work environments. In addition, cognitive functioning also plays an important role in sports. Various cognitive skills, including attention, reaction time and motor function, have shown that they can influence sport performance. A completely natural supplement with aronia melanocarpa extract could be a promising way to naturally improve cognitive performance. The product in this study is aronia melanocarpa which contains polyphenols. A limited number of clinical studies have already been carried out to see the effect of similar products on cognitive functioning. However, these studies have often been done in older study populations or over a longer period of time. In this study, in healthy adolescents (ages between the 18-35 and with a BMI between 18.5 and 30), the investigators want to test the short term (7 days) effect of aronia melanocarpa extract on cognitive functioning. The investigators will also test the effect of supplementation on the particpant's mood, vascular function, blood biomarkers, retinal vasculature, and subjective cognition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| placebo | Placebo Comparator | microcrystalline cellulose supplementation |
|
| Aronia | Experimental | aronia melanocarpa supplementation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aronia | Dietary Supplement | daily supplementation |
| |
| Placebo |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive function | CANTAB | After 7 days of supplementation |
| Measure | Description | Time Frame |
|---|---|---|
| Mood | VAMS | After 7 days of supplementation |
| Biomarkers in blood and saliva | BDNF & cortisol | After 7 days of supplementation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jogchum Plat, Prof | Maastricht University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maastricht University | Maastricht | Limburg | 6229ET | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38656355 | Derived | Ahles S, Joris PJ, Plat J. Short-term Aronia melanocarpa extract supplementation improves cognitive performance: a randomized, double-blind, placebo-controlled cross-over study in healthy young adults. Eur J Nutr. 2024 Aug;63(5):1545-1553. doi: 10.1007/s00394-024-03381-3. Epub 2024 Apr 24. |
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Cross-over study with 2 intervention conditions
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block randomization
| Dietary Supplement |
daily supplementation |
|
| Vascular function | SBP & DBP, PWA & PWV | After 7 days of supplementation |
| Microvasculature | Fundus photography | After 7 days of supplementation |
| Subjective cognition | Cognitive Failures Questionnaire | After 7 days of supplementation |