Comparison Between Drugs for Control of Emetic Attacks During Caesarean Delivery

Comparison Between Propofol, Ondansetron and Pregabalin for Control of Emetic Attacks During Caesarean Delivery With Spinal Anesthesia: Randomized Clinical Trial

Single shot spinal anesthesia is widely used for most surgical operations especially in obstetric such as hysterectomy, tubal ligation after vaginal delivery, cesarean and curettage etc.; however, in general, cesarean is considered as the most common indication for spinal anesthesia in pregnant women Intra-operative nausea and vomiting/retching (NVR) may be experienced by 20% to 80% of women undergoing cesarean section (CS) with subarachnoid anesthesia (SA) in the absence of antiemetic prophylaxis.

Different treatment options are available to reduce post operative nausea and vomiting (PONV) so we will make a Comparison between Propofol, Ondansetron and Pregabalin for Control of Emetic Attacks during Caesarean Delivery with Spinal Anesthesia

Inclusion Criteria:

• Age: 21-40 years old.
• Physical status American Society of Anesthesiologists (ASA)I&II.
• Body mass index (BMI) < 35&>20 kg/m2.
• Elective uncomplicated cesarean section under spinal anesthesia.

Exclusion Criteria:

• Patient refusal.
• Patients with known history of allergy to study drugs.
• Advanced hepatic, renal and respiratory diseases.
• Psychological and mental disorders.
• Patient with reduced level of consciousness.
• Hypertensive, cardiac, and diabetic patients.
• Patients receiving anticoagulants therapy or suspected coagulopathy.