Cetylated Fatty Acid for Reducing Pain After TKA

Efficacy of Cetylated Fatty Acid for Alleviating Postoperative Pain After Total Knee Arthroplasty: A Randomized Placebo-controlled Trial

To compare efficacy of cetylated fatty acid with placebo for reducing postoperative pain after unilateral TKA. The hypothesis is topical cetylated fatty acid can mitigate postoperative pain after TKA.

Inclusion Criteria:

• Age 50-80 years
• Osteoarthritic knee patients underwent unilateral primary TKA
• Participants understand and consent to the protocol of the trial

Exclusion Criteria:

• Inflammatory knee arthritis
• Previous knee surgery or trauma
• Previous knee infection
• Skin problem around the knee such as eczema, psoriasis, wound infection
• Allergy to studied drug