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The primary objectives of the present study are to estimate the sarcopenic proportion in a cohort of obese older subjects who have been hospitalized. The secondary objective is to individuate several clinical variables that differ between the sarcopenic obese patient and the not sarcopenic obese patient.
80 obese patients of both genders (BMI > 35), with an age > 60 years, hospitalized at the Hospital San Giuseppe, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB) are selected. For each patient, the following information are collected at the time of admission:
The presence of sarcopenia is identified based on the European Working Group on Sarcopenia in Older People (EWGSOP2) (Cruz-Jentoft AJ et al. 2019) definition. The physical performance parameters is evaluated according to the age, sex, obesity grade, and presence of sarcopenic obesity.
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| Measure | Description | Time Frame |
|---|---|---|
| Fat free mass | Measurement of body composition parameters with bioimpedance analysis (BIA) and DEXA | Baseline |
| Evaluation of lower limb muscle strength | Measurement with the stair climbing test | Baseline |
| Senior Fitness Test (SFT) | A battery of tests useful to estimate the fitness level of the elderly. This is a test that allows measuring different physical parameters typical of daily activities: strength of upper and lower limbs, aerobic resistance, flexibility of lower and upper limbs, agility, and dynamic equilibrium. | Baseline |
| Physical performance test (PPT) | A test evaluating 7 physical capabilities areas of the subject to perform actions during daily life. The cut-off to determine the motor limitation condition is a score of ≤ 20 (out of 28 points). | Baseline |
| Fat mass | Measurement of body composition parameters with bioimpedance analysis (BIA) and DEXA; | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Questionnaire SF-12 (Short Form Health Survey) | A questionnaire allowing a multi-dimensional measurement of quality of life related to health. It is composed of 12 questions from which it is possible obtaining two synthetic indexes, one related to physical health and the other one related to mental health. | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Obese patients (BMI > 35), of both genders, aged > 60 years, hospitalized at San Giuseppe Hospital, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy for a multidisciplinary 3-week body weight reduction program.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istituto Auxologico Italiano, Site Piancavallo | Oggebbio | Verbania | 28824 | Italy |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D055948 | Sarcopenia |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| Oswestry Disability Index questionnaire |
A questionnaire elaborated to have information on how back problems, or leg problems, can influence physical abilities related to daily life. |
| Baseline |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009133 | Muscular Atrophy |
| D020879 | Neuromuscular Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D001284 | Atrophy |
| D020763 | Pathological Conditions, Anatomical |