The aim of this study was to measure the acute change in oxygen saturation of skeletal muscle during resistance exercise in the upper extremity using near-infrared spectroscopy.

Our study aims to determine the acute oxygen response in the upper extremity muscles against a resistance exercise fatigue protocol, in order to demonstrate the effect of muscle oxygenation levels on the occurrence of symptoms such as fatigue in upper extremity use, and to provide reference information for the development of exercise programs.

It is known that resistance exercise increases resting energy expenditure and promotes fat oxidation for weight loss. Changes in cardiopulmonary function that occur in chronic diseases reduce oxygen uptake and decrease energy production, leading to increased fatigue. Resistance exercises in chronic diseases can regulate an individual's energy production capacity.

The main objective of our study is to investigate the effect of muscle oxygenation levels on the occurrence of symptoms such as fatigue by determining the oxygen response in the upper extremity muscles based on a resistance exercise protocol.

Inclusion Criteria:

• Volunteering to participate in the study
• Being over 18 years old
• Having a Body Mass Index (BMI) value between 23-30 kg/m2
• Absence of comorbid disease of the orthopedic, neurological, cardiopulmonery system

Exclusion Criteria:

• Smoking / alcohol use
• Presence of orthopedic disease effecting the upper extremity or previous surgery
• Presence of cardiopulmonery disease that prevents exercise
• Participants who performed resistance exercise regulary for more than 6 months