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| Name | Class |
|---|---|
| Hochschule Furtwangen University | OTHER |
| Budapest University of Technology and Economics | OTHER |
| Szeged University | OTHER |
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Patient-ventilator asynchrony (PVA) has deleterious effects on the lungs. PVA can lead to acute lung injury and worsening hypoxemia through biotrauma. Little is known about how PVA affects lung aeration estimated by electric impedance tomography (EIT). Artificial intelligence can promote the detection of PVA and with its help, EIT measurements can be correlated to asynchrony.
Patient-ventilator asynchrony (PVA) is a common phenomenon with invasively- and non-invasively ventilated patients. PVA has deleterious effects on the lungs. It causes not just patient discomfort and distress but also leads to acute lung injury and worsening hypoxemia through biotrauma. The latter significantly impacts outcomes and increases the duration of mechanical ventilation and intensive care unit stay.
However, PVA is a widely investigated incident related to mechanical ventilation, though little is known about how it affects lung aeration estimated by electric impedance tomography (EIT). EIT is a non-invasive, real-time monitoring technique suitable for detecting changes in lung volumes during ventilation.
Artificial intelligence can promote the detection of PVA by flow versus time assessment. If continuous EIT recording is correlated with the latter, impedance tomography changes evoked by asynchrony can be estimated
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| mechanically ventilated patients | Invasively or non-invasively ventilated patients. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| EIT | Device | continuous electric impedance tomography measurement |
| |
| Measure | Description | Time Frame |
|---|---|---|
| distribution | gas distribution in lungs assessed by electric impedance tomography | during mechanical ventilation |
| Measure | Description | Time Frame |
|---|---|---|
| connecting asysnchrony cycles with electric impedance tomography measurements | connecting machine learning assessed patient-ventilator asynchrony respiratory cycles with the inherent respiratory cycle recorded by the electric impedance tomography | during mechanical ventilation |
| identifying unic electric impedance tomography signs of asynchrony |
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Inclusion Criteria:
Exclusion Criteria:
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mechanically ventilated patients
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| AndrĂ¡s Lovas, M.D. Ph.D. | Contact | 003677522000 | 2045 | landras@halasi-korhaz.hu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kiskunhalas Semmelweis Hopsital the Teaching Hospital of the University of Szeged | Kiskunhalas | 6400 | Hungary |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33381233 | Result | Sottile PD, Albers D, Smith BJ, Moss MM. Ventilator dyssynchrony - Detection, pathophysiology, and clinical relevance: A Narrative review. Ann Thorac Med. 2020 Oct-Dec;15(4):190-198. doi: 10.4103/atm.ATM_63_20. Epub 2020 Oct 10. | |
| 30360753 | Result | Bachmann MC, Morais C, Bugedo G, Bruhn A, Morales A, Borges JB, Costa E, Retamal J. Electrical impedance tomography in acute respiratory distress syndrome. Crit Care. 2018 Oct 25;22(1):263. doi: 10.1186/s13054-018-2195-6. |
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| ID | Term |
|---|---|
| D055371 | Acute Lung Injury |
| D000097742 | Patient-Ventilator Asynchrony |
| ID | Term |
|---|---|
| D055370 | Lung Injury |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D012131 | Respiratory Insufficiency |
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| patient-ventilator asynchrony assessment |
| Device |
patient-ventilator asynchrony assessment by flow/time curve and machine learning |
|
following connection described under "outcome 2", identification if single patient-ventilator asynchrony types (delayed cycling, premature cycling, auto trigger, ineffective effort, double trigger) present specific electric impedance tomography changes |
| during mechanical ventilation |
| D012120 |
| Respiration Disorders |
| D012818 | Signs and Symptoms, Respiratory |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |